When your dog is panting, not eating, and has diarrhea, it’s a strong indication that something is seriously wrong.
These three symptoms together suggest that your dog is not only uncomfortable but likely dealing with a health issue that affects multiple systems—often the digestive and nervous systems.
We outline the common causes of dog panting, not eating, and diarrhea, what you can do at home, and when to seek veterinary help.
Dog Panting, Not Eating, Diarrhea: Why It Happens
When your dog is panting, not eating, and has diarrhea, the underlying cause is often gastrointestinal in nature—such as a viral or bacterial infection, dietary indiscretion, food intolerance, or parasites. But it can also be linked to pain, anxiety, toxin exposure, pancreatitis, or inflammatory diseases.
The panting reflects discomfort or fever, the refusal to eat suggests nausea or abdominal cramping, and diarrhea is the body’s way of purging something harmful. Let’s look closer at the most likely causes.

Dog Panting, Not Eating, Diarrhea: Common Causes
Gastrointestinal Infections
Viruses like parvovirus or bacteria such as salmonella can wreak havoc on your dog’s digestive tract.
Panting may accompany the fever or abdominal pain these infections cause.
Diarrhea can be watery or bloody, and loss of appetite is common due to nausea. Puppies and unvaccinated dogs are especially at risk.
These cases require immediate veterinary care and often hospitalization for fluids and supportive treatment.
Dietary Indiscretion or Sudden Diet Change
Many dogs develop digestive upset after eating something they shouldn’t—like garbage, fatty foods, or spoiled meat.
This “dietary indiscretion” can cause diarrhea, abdominal pain, and nausea, which leads to panting and a refusal to eat.
Similarly, changing your dog’s food too quickly can upset the digestive balance, especially in sensitive stomachs.
Mild cases may resolve in 24 hours, but if symptoms persist or worsen, it’s time to call the vet.
Related: Dog diarrhea and not eating (Causes and when to worry)
Pancreatitis
Panting, diarrhea, and appetite loss are hallmark symptoms of pancreatitis—inflammation of the pancreas.
This condition often occurs after a dog consumes a fatty meal or treats like bacon or table scraps.
Dogs with pancreatitis may also vomit or seem hunched and restless.
Miniature Schnauzers and other small breeds are especially susceptible. This condition can be life-threatening if not treated early.
Stress or Anxiety
Some dogs respond to emotional distress with physical symptoms like panting and diarrhea.
A move, loud noise, vet visit, or separation from their owner may trigger gastrointestinal upset and a refusal to eat.
While stress-induced diarrhea is usually short-lived, if panting continues or your dog becomes lethargic, medical intervention may be necessary to rule out other causes.
Parasites
Intestinal parasites like Giardia, hookworms, or roundworms can cause diarrhea, appetite loss, and discomfort.
Puppies and recently rescued dogs are at higher risk. These parasites irritate the gastrointestinal tract, leading to cramps (which cause panting), as well as poor nutrient absorption.
A fecal exam is needed to confirm diagnosis, and treatment is typically straightforward with deworming medications.
Food Allergies or Sensitivities
Some dogs develop food allergies or intolerances that cause chronic diarrhea, vomiting, and even skin irritation.
A dog experiencing a flare-up may begin to pant due to stomach cramps or itchy skin and avoid food due to discomfort.
If symptoms repeat after eating certain proteins (like chicken, beef, or grains), consult your vet about switching to a limited-ingredient or hypoallergenic diet.
Toxin Ingestion
Toxins can cause vomiting, diarrhea, excessive panting, and rapid deterioration.
If your dog has ingested something poisonous—like medications, chocolate, xylitol, or cleaning products—they may also appear weak or disoriented.
These cases are time-sensitive. If you suspect poisoning, do not wait; contact your vet or an emergency clinic immediately.
Inflammatory Bowel Disease (IBD)
Chronic diarrhea and food refusal can be signs of IBD—a condition in which the digestive tract becomes inflamed over time.
Dogs with IBD may also experience weight loss, gas, and intermittent vomiting. Panting may be a sign of ongoing abdominal discomfort.
Diagnosis often involves blood tests, ultrasounds, and sometimes biopsies. Treatment includes special diets and medication.
What to Do If Dog Panting, Not Eating, Diarrhea Happens
Start by removing food for 12 hours to allow the digestive system to rest, but continue to offer water or an electrolyte solution to prevent dehydration.
Monitor your dog’s temperature and behavior. If diarrhea is mild and your dog seems otherwise alert, you can try introducing a bland diet of boiled chicken and rice in small portions.
However, if panting is persistent, diarrhea is severe or bloody, or your dog becomes lethargic or refuses water, you should not wait.
These signs can indicate rapid fluid loss, internal inflammation, or systemic infection—and early treatment is crucial.
When to Call or Visit Your Vet
You should seek veterinary care immediately if:
Diarrhea continues for more than 24 hours
Your dog refuses food and water
Panting occurs even at rest
Vomiting accompanies the diarrhea
There’s blood in the stool
Your dog seems weak, disoriented, or dehydrated
You suspect your dog ingested something toxic
Even a few hours of diarrhea and food refusal can lead to dehydration, especially in puppies and senior dogs.
Read more: Dog panting throwing up, and not eating (Here’s why)
Key Takeaway
When your dog is panting, not eating, and has diarrhea, it’s a combination of symptoms you should never ignore.
These signs point to significant discomfort and often signal a deeper health problem—ranging from mild stress to serious illness.
Your dog is depending on you to notice the warning signs and respond appropriately.
Don’t try to self-diagnose or treat serious cases at home. Always consult your vet if symptoms persist, worsen, or come on suddenly.
With quick care and proper treatment, most dogs recover well and return to their normal, happy selves.